Research Program in Genome-Scale Biology

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  1. 2012
  2. Anti-Mullerian hormone as a predictor of follicular reserve in ovarian insufficiency: special emphasis on FSH-resistant ovaries

    Kallio, S., Aittomäki, K., Piltonen, T., Veijola, R., Liakka, A., Vaskivuo, T. E., Dunkel, L. & Tapanainen, J. S. 2012 In : Human Reproduction. 27, 3, p. 854-860 7 p.

    Publication: Contribution to journalA1 Refereed journal article

  3. Association between IL6-174G/C and cancer: A meta-analysis of 105,482 individuals

    Liu, R-Y., Song, X., Chen, P., Lei, Z., Miao, J., Yi, N., Zhang, K., Pasche, B. & Zhang, H-T. 2012 In : Experimental and therapeutic medicine. 3, 4, p. 655-664 10 p.

    Publication: Contribution to journalA1 Refereed journal article

  4. Bioinformatic identification of genomic alterations in breast cancer

    Edgren, H. 2012 Helsinki: [H. Edgren]. 75 p.

    Publication: Book/anthologyG5 Doctoral Thesis, articles

  5. Breast carcinoma and Lynch syndrome: molecular analysis of tumors arising in mutation carriers, non-carriers, and sporadic cases

    Lotsari, J. E., Gylling, A., Abdel-Rahman, W. M., Nieminen, T. T., Aittomaki, K., Friman, M., Pitkanen, R., Aarnio, M., Jarvinen, H. J., Mecklin, J-P., Kuopio, T. & Peltomaki, P. 2012 In : Breast Cancer Research. 14, 3, p. - 11 p.

    Publication: Contribution to journalA1 Refereed journal article

  6. CIP2A overexpression is associated with c-Myc expression in colorectal cancer

    Böckelman, C., Koskensalo, S., Hagström, J., Lundin, M. E., Ristimäki, A. & Haglund, C. 2012 In : Cancer Biology & Therapy. 13, 5, p. 289 - 295 7 p.

    Publication: Contribution to journalA1 Refereed journal article

  7. Candidate driver genes in microsatellite-unstable colorectal cancer

    Alhopuro, P. P., Sammalkorpi, H. P., Niittymäki, I., Biström, M., Raitila, A., Saharinen, J. M. N., Nousiainen, K. J., Lehtonen, H., Heliövaara, E., Puhakka, J., Tuupanen, S., Sousa, S., Seruca, R., Ferreira, A. M., Hofstra, R. M. W., Mecklin, J-P., Järvinen, H., Ristimäki, A., Orntoft, T. F., Hautaniemi, S., Arango, D., Karhu, A. I. & Aaltonen, L. A. 2012 In : International Journal of Cancer. 130, 7, p. 1558–1566 9 p.

    Publication: Contribution to journalA1 Refereed journal article

  8. Characterization of the colorectal cancer-associated enhancer MYC-335 at 8q24: the role of rs67491583

    Tuupanen, S., Yan, J., Turunen, M., Gylfe, A. E., Kaasinen, E., Li, L., Eng, C., Culver, D. A., Kalady, M. F., Pennison, M. J., Pasche, B., Manne, U., de la Chapelle, A., Hampel, H., Henderson, B. E., Le Marchand, L., Hautaniemi, S., Askhtorab, H., Smoot, D., Sandler, R. S., Keku, T., Kupfer, S. S., Ellis, N. A., Haiman, C. A., Taipale, J. & Aaltonen, L. A. 2012 In : Cancer Genetics. 205, 1-2, p. 25-33 9 p.

    Publication: Contribution to journalA1 Refereed journal article

  9. Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

    Dunlop, M. G., Dobbins, S. E., Farrington, S. M., Jones, A. M., Palles, C., Whiffin, N., Tenesa, A., Spain, S., Broderick, P., Ooi, L-Y., Domingo, E., Smillie, C., Henrion, M., Frampton, M., Martin, L., Grimes, G., Gorman, M., Semple, C., Ma, Y. P., Barclay, E., Prendergast, J., Cazier, J-B., Olver, B., Penegar, S., Lubbe, S., Chander, I., Carvajal-Carmona, L. G., Ballereau, S., Lloyd, A., Vijayakrishnan, J., Zgaga, L., Rudan, I., Theodoratou, E., Starr, J. M., Deary, I., Kirac, I., Kovacevic, D., Aaltonen, L. A., Renkonen-Sinisalo, L., Mecklin, J-P., Matsuda, K., Nakamura, Y., Okada, Y., Gallinger, S., Duggan, D. J., Conti, D., Newcomb, P., Hopper, J., Jenkins, M. A., Schumacher, F., Casey, G., Easton, D., Shah, M., Pharoah, P., Lindblom, A., Liu, T., Smith, C. G., West, H., Cheadle, J. P., Midgley, R., Kerr, D. J., Campbell, H., Tomlinson, I. P., Houlston, R. S. & Swedish Low-Risk Colorectal Canc, Coin Collaborative Grp, Colorectal Tumour Gene Identificat 2012 In : Nature Genetics. 44, 7, p. 770-U197 9 p.

    Publication: Contribution to journalA1 Refereed journal article

  10. Comparative analysis of algorithms for integration of copy number and expression data

    Louhimo, R., Lepikhova, T., Monni, O. & Hautaniemi, S. 2012 In : Nature methods.. 9, 4, p. 351-U50 9 p.

    Publication: Contribution to journalA1 Refereed journal article

  11. Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

    Hein, R., Maranian, M., Hopper, J. L., Kapuscinski, M. K., Southey, M. C., Park, D. J., Schmidt, M. K., Broeks, A., Hogervorst, F. B. L., Bueno-de-Mesquit, H. B., Muir, K. R., Lophatananon, A., Rattanamongkongul, S., Puttawibul, P., Fasching, P. A., Hein, A., Ekici, A. B., Beckmann, M. W., Fletcher, O., Johnson, N., Silva, I. D. S., Peto, J., Sawyer, E., Tomlinson, I., Kerin, M., Miller, N., Marmee, F., Schneeweiss, A., Sohn, C., Burwinkel, B., Guenel, P., Cordina-Duverger, E., Menegaux, F., Truong, T., Bojesen, S. E., Nordestgaard, B. G., Flyger, H., Milne, R. L., Arias Perez, J. I., Pilar Zamora, M., Benitez, J., Anton-Culver, H., Ziogas, A., Bernstein, L., Clarke, C. A., Brenner, H., Mueller, H., Arndt, V., Stegmaier, C., Rahman, N., Seal, S., Turnbull, C., Renwick, A., Meindl, A., Schott, S., Bartram, C. R., Schmutzler, R. K., Brauch, H., Hamann, U., Ko, Y-D., Wang-Gohrke, S., Doerk, T., Schuermann, P., Karstens, J. H., Hillemanns, P., Nevanlinna, H., Heikkinen, T., Aittomäki, K., Blomqvist, C., Bogdanova, N. V., Zalutsky, I. V., Antonenkova, N. N., Bermisheva, M., Prokovieva, D., Farahtdinova, A., Khusnutdinova, E., Lindblom, A., Margolin, S., Mannermaa, A., Kataja, V., Kosma, V-M., Hartikainen, J., Chen, X., Beesley, J., Lambrechts, D., Zhao, H., Neven, P., Wildiers, H., Nickels, S., Flesch-Janys, D., Radice, P., Peterlongo, P., Manoukian, S., Barile, M., Couch, F. J., Olson, J. E., Wang, X., Fredericksen, Z., Giles, G. G., Baglietto, L., McLean, C. A., Severi, G., Offit, K., Robson, M., Gaudet, M. M., Vijai, J., Alnaes, G. G., Kristensen, V., Borresen-Dale, A-L., John, E. M., Miron, A., Winqvist, R., Pylkas, K., Jukkola-Vuorinen, A., Grip, M., Andrulis, I. L., Knight, J. A., Glendon, G., Mulligan, A. M., Figueroa, J. D., Garcia-Closas, M., Lissowska, J., Sherman, M. E., Hooning, M., Martens, J. W. M., Seynaeve, C., Collee, M., Hall, P., Humpreys, K., Czene, K., Liu, J., Cox, A., Brock, I. W., Cross, S. S., Reed, M. W. R., Ahmed, S., Ghoussaini, M., Pharoah, P. D. P., Kang, D., Yoo, K-Y., Noh, D-Y., Jakubowska, A., Jaworska, K., Durda, K., Zlowocka, E., Sangrajrang, S., Gaborieau, V., Brennan, P., McKay, J., Shen, C-Y., Yu, J-C., Hsu, H-M., Hou, M-F., Orr, N., Schoemaker, M., Ashworth, A., Swerdlow, A., Trentham-Dietz, A., Newcomb, P. A., Titus, L., Egan, K. M., Chenevix-Trench, G., Antoniou, A. C., Humphreys, M. K., Morrison, J., Chang-Claude, J., Easton, D. F., Dunning, A. M., Network, G. E. N. I. C. A., Investigators, KC. & Grp, A. O. C. S. 2012 In : PLoS One. 7, 8, p. Article Number: e42380 14 p.

    Publication: Contribution to journalA1 Refereed journal article