Research Program in Genome-Scale Biology

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  1. 2012
  2. ErbB2-Driven Breast Cancer Cell Invasion Depends on a Complex Signaling Network Activating Myeloid Zinc Finger-1-Dependent Cathepsin B Expression

    Rafn, B., Nielsen, C. F., Andersen, S. H., Szyniarowski, P., Corcelle-Termeau, E., Valo, E., Fehrenbacher, N., Olsen, C. J., Daugaard, M., Egebjerg, C., Bottzauw, T., Kohonen, P., Nylandsted, J., Hautaniemi, S., Moreira, J., Jaattela, M. & Kallunki, T. 2012 In : Molecular Cell. 45, 6, p. 764-776 13 p.

    Publication: Contribution to journalA1 Refereed journal article

  3. Genome-wide association analysis identifies three new breast cancer susceptibility loci

    Ghoussaini, M., Fletcher, O., Michailidou, K., Turnbull, C., Schmidt, M. K., Dicks, E., Dennis, J., Wang, Q., Humphreys, M. K., Luccarini, C., Baynes, C., Conroy, D., Maranian, M., Ahmed, S., Driver, K., Johnson, N., Orr, N., Silva, I. D. S., Waisfisz, Q., Meijers-Heijboer, H., Uitterlinden, A. G., Rivadeneira, F., Hall, P., Czene, K., Irwanto, A., Liu, J., Nevanlinna, H., Aittomaki, K., Blomqvist, C., Meindl, A., Schmutzler, R. K., Mueller-Myhsok, B., Lichtner, P., Chang-Claude, J., Hein, R., Nickels, S., Flesch-Janys, D., Tsimiklis, H., Makalic, E., Schmidt, D., Bui, M., Hopper, J. L., Apicella, C., Park, D. J., Southey, M., Hunter, D. J., Chanock, S. J., Broeks, A., Verhoef, S., Hogervorst, F. B. L., Fasching, P. A., Lux, M. P., Beckmann, M. W., Ekici, A. B., Sawyer, E., Tomlinson, I., Kerin, M., Marme, F., Schneeweiss, A., Sohn, C., Burwinkel, B., Guenal, P., Truong, T., Cordina-Duverger, E., Menegaux, F., Bojesen, S. E., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Milne, R. L., Rosario Alonso, M., Gonzalez-Neira, A., Benitez, J., Anton-Culver, H., Ziogas, A., Bernstein, L., Dur, C. C., Brenner, H., Mueller, H., Arndt, V., Stegmaier, C., Justenhoven, C., Brauch, H., Bruening, T., Wang-Gohrke, S., Eilber, U., Doerk, T., Schuermann, P., Bremer, M., Hillemanns, P., Bogdanova, N. V., Antonenkova, N. N., Rogov, Y. I., Karstens, J. H., Bermisheva, M., Prokofieva, D., Khusnutdinova, E., Lindblom, A., Margolin, S., Mannermaa, A., Kataja, V., Kosma, V-M., Hartikainen, J. M., Lambrechts, D., Yesilyurt, B. T., Floris, G., Leunen, K., Manoukian, S., Bonanni, B., Fortuzzi, S., Peterlongo, P., Couch, F. J., Wang, X., Stevens, K., Lee, A., Giles, G. G., Baglietto, L., Severi, G., McLean, C., Alnaes, G. G., Kristensen, V., Borrensen-Dale, A-L., John, E. M., Miron, A., Winqvist, R., Pylkas, K., Jukkola-Vuorinen, A., Kauppila, S., Andrulis, I. L., Glendon, G., Mulligan, A. M., Devilee, P., van Asperen, C. J., Tollenaar, R. A. E. M., Seynaeve, C., Figueroa, J. D., Garcia-Closas, M., Brinton, L., Lissowska, J., Hooning, M. J., Hollestelle, A., Oldenburg, R. A., van den Ouweland, A. M. W., Cox, A., Reed, M. W. R., Shah, M., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Jones, M., Schoemaker, M., Ashworth, A., Swerdlow, A., Beesley, J., Chen, X., Muir, K. R., Lophatananon, A., Rattanamongkongul, S., Chaiwerawattana, A., Kang, D., Yoo, K-Y., Noh, D-Y., Shen, C-Y., Yu, J-C., Wu, P-E., Hsiung, C-N., Perkins, A., Swann, R., Velentzis, L., Eccles, D. M., Tapper, W. J., Gerty, S. M., Graham, N. J., Ponder, B. A. J., Chenevix-Trench, G., Pharoah, P. D. P., Lathrop, M., Dunning, A. M., Rahman, N., Peto, J., Easton, D. F. & FBCS, Gene Environm Interaction Breast C, kConFab Investigators, Netherlands Collaborative Grp Here, Australian Ovarian Canc Study Grp 2012 In : Nature Genetics. 44, 3, p. 312-U120 8 p.

    Publication: Contribution to journalA1 Refereed journal article

  4. Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation

    Mathiasen, D. P., Egebjerg, C., Andersen, S. H., Rafn, B., Puustinen, P., Khanna, A., Daugaard, M., Valo, E., Tuomela, S., Bottzauw, T., Nielsen, C. F., Willumsen, B. M., Hautaniemi, S., Lahesmaa, R., Westermarck, J., Jaattela, M. & Kallunki, T. 2012 In : Oncogene. 31, p. 390-401 12 p.

    Publication: Contribution to journalA1 Refereed journal article

  5. Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus

    Diaconu, I., Cerullo, V., Hirvinen, M. L. M., Escutenaire, S., Ugolini, M., Pesonen, S. K., Bramante, S., Parviainen, S., Kanerva, A-M., Loskog, A. S. I., Eliopoulos, A. G., Pesonen, S. & Hemminki, A. 2012 In : Cancer Research. 72, 9, p. 2327-2338 12 p.

    Publication: Contribution to journalA1 Refereed journal article

  6. Impact of Epithelial Organization on Myc Expression and Activity

    Partanen, J. I. & Klefstrom, J. 2012 In : Cancer Research. 72, 4, p. 1035-1035 1 p.

    Publication: Contribution to journalB1 Unrefereed journal article

  7. Inhibition of cyclooxygenase-2 causes regression of gastric adenomas in trefoil factor 1 deficient mice

    Thiel, A., Narko, K., Heinonen, M., Hemmes, A., Tomasetto, C., Rio, M-C., Haglund, C., Mäkelä, T. P. & Ristimäki, A. 2012 In : International Journal of Cancer. 131, 5, p. 1032-1041 10 p.

    Publication: Contribution to journalA1 Refereed journal article

  8. Integrative transcriptional analysis between human and mouse cancer cells provides a common set of transformation associated genes

    Balestrieri, C., Vanoni, M., Hautaniemi, S., Alberghina, L. & Chiaradonna, F. 2012 In : Biotechnology Advances. 30, 1, p. 16-29 14 p.

    Publication: Contribution to journalA1 Refereed journal article

  9. Interaction with ErbB4 Promotes Hypoxia-inducible Factor-1 alpha Signaling

    Paatero, I., Jokilammi, A., Heikkinen, P. T., Iljin, K., Kallioniemi, O-P., Jones, F. E., Jaakkola, P. M. & Elenius, K. 2012 In : Journal of Biological Chemistry. 287, 13, p. 9659-9671 13 p.

    Publication: Contribution to journalA1 Refereed journal article

  10. Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Interacts with Multifunctional Angiogenin To Utilize Its Antiapoptotic Functions

    Paudel, N., Sadagopan, S., Chakraborty, S., Sarek, G., Ojala, P. & Chandran, B. 2012 In : Journal of Virology. 86, 11, p. 5974-5991 18 p.

    Publication: Contribution to journalA1 Refereed journal article

  11. Kystä kyllin

    Saxen, H., Mäkelä, T., Saarelma, O. & Pelkonen, R. 2012 In : Duodecim. 127, 23, p. 2394-2395 2 p.

    Publication: Contribution to journalB1 Unrefereed journal article