Research Program in Genome-Scale Biology

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  1. 2012
  2. 19p13.1 Is a Triple-Negative-Specific Breast Cancer Susceptibility Locus

    Stevens, K. N., Fredericksen, Z., Vachon, C. M., Wang, X., Margolin, S., Lindblom, A., Nevanlinna, H., Greco, D., Aittomaki, K., Blomqvist, C., Chang-Claude, J., Vrieling, A., Flesch-Janys, D., Sinn, H-P., Wang-Gohrke, S., Nickels, S., Brauch, H., Ko, Y-D., Fischer, H-P., Schmutzler, R. K., Meindl, A., Bartram, C. R., Schott, S., Engel, C., Godwin, A. K., Weaver, J., Pathak, H. B., Sharma, P., Brenner, H., Mueller, H., Arndt, V., Stegmaier, C., Miron, P., Yannoukakos, D., Stavropoulou, A., Fountzilas, G., Gogas, H. J., Swann, R., Dwek, M., Perkins, A., Milne, R. L., Benitez, J., Pilar Zamora, M., Arias Perez, J. I., Bojesen, S. E., Nielsen, S. F., Nordestgaard, B. G., Flyger, H., Guenel, P., Truong, T., Menegaux, F., Cordina-Duverger, E., Burwinkel, B., Marme, F., Schneeweiss, A., Sohn, C., Sawyer, E., Tomlinson, I., Kerin, M. J., Peto, J., Johnson, N., Fletcher, O., dos Santos Silva, I., Fasching, P. A., Beckmann, M. W., Hartmann, A., Ekici, A. B., Lophatananon, A., Muir, K., Puttawibul, P., Wiangnon, S., Schmidt, M. K., Broeks, A., Braaf, L. M., Rosenberg, E. H., Hopper, J. L., Apicella, C., Park, D. J., Southey, M. C., Swerdlow, A. J., Ashworth, A., Orr, N., Schoemaker, M. J., Anton-Culver, H., Ziogas, A., Bernstein, L., Dur, C. C., Shen, C-Y., Yu, J-C., Hsu, H-M., Hsiung, C-N., Hamann, U., Duennebier, T., Ruediger, T., Ulmer, H. U., Pharoah, P. P., Dunning, A. M., Humphreys, M. K., Wang, Q., Cox, A., Cross, S. S., Reed, M. W., Hall, P., Czene, K., Ambrosone, C. B., Ademuyiwa, F., Hwang, H., Eccles, D. M., Garcia-Closas, M., Figueroa, J. D., Sherman, M. E., Lissowska, J., Devilee, P., Seynaeve, C., Tollenaar, R. A. E. M., Hooning, M. J., Andrulis, I. L., Knight, J. A., Glendon, G., Mulligan, A. M., Winqvist, R., Pylkas, K., Jukkola-Vuorinen, A., Grip, M., John, E. M., Miron, A., Alnaes, G. G., Kristensen, V., Borresen-Dale, A-L., Giles, G. G., Baglietto, L., McLean, C. A., Severi, G., Kosel, M. L., Pankratz, V. S., Slager, S., Olson, J. E., Radice, P., Peterlongo, P., Manoukian, S., Barile, M., Lambrechts, D., Hatse, S., Dieudonne, A-S., Christiaens, M-R., Chenevix-Trench, G., Beesley, J., Chen, X., Mannermaa, A., Kosma, V-M., Hartikainen, J. M., Soini, Y., Easton, D. F., Couch, F. J. & AOCS Grp, kConFab Investigators, GENICA Network 2012 In : Cancer Research. 72, 7, p. 1795-1803 9 p.

    Publication: Contribution to journalA1 Refereed journal article

  3. A Boolean Approach for Disentangling the Roles of Submodules to the Global Properties of a Biomodel

    Czeizler, E. & Petre, I. 2012 In : Fundamenta Informaticae. 116, 1-4, p. 51-63 13 p.

    Publication: Contribution to journalA1 Refereed journal article

  4. A Finnish founder mutation in RAD51D: analysis in breast, ovarian, prostate, and colorectal cancer

    Pelttari, L. M., Kiiski, J., Nurminen, R., Kallioniemi, A., Schleutker, J., Gylfe, A., Aaltonen, L. A., Leminen, A., Heikkilä, P., Blomqvist, C., Butzow, R., Aittomäki, K. & Nevanlinna, H. 2012 In : Journal of Medical Genetics. 49, 7, p. 429-432 4 p.

    Publication: Contribution to journalA1 Refereed journal article

  5. A Nonsynonymous Polymorphism in IRS1 Modifies Risk of Developing Breast and Ovarian Cancers in BRCA1 and Ovarian Cancer in BRCA2 Mutation Carriers

    Nevanlinna, H., Aittomäki, K. & SWE-BRCA, HEBON, EMBRACE, GEMO Study Collaborators, KConFab Investigators, OCGN, Consortium Investigators Modifiers 2012 In : Cancer Epidemiology, Biomarkers & Prevention. 21, 8, p. 1362-1370 9 p.

    Publication: Contribution to journalA1 Refereed journal article

  6. A functional genetic screen reveals new regulators of beta 1-integrin activity

    Pellinen, T., Rantala, J. K., Arjonen, A., Mpindi, J. P., Kallioniemi, O. & Ivaska, J. 2012 In : Journal of Cell Science. 125, 3, p. 649-661 13 p.

    Publication: Contribution to journalA1 Refereed journal article

  7. An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer

    Mamo, A., Cavallone, L., Tuzmen, S., Chabot, C., Ferrario, C., Hassan, S., Edgren, H., Kallioniemi, O., Aleynikova, O., Przybytkowski, E., Malcolm, K., Mousses, S., Tonin, P. N. & Basik, M. 2012 In : Oncogene. 31, 16, p. 2090-2100 11 p.

    Publication: Contribution to journalA1 Refereed journal article

  8. An optimized isolation of biotinylated cell surface proteins reveals novel players in cancer metastasis

    Karhemo, P-R., Ravela, S., Laakso, M., Ritamo, I., Tatti, O., Mäkinen, S., Goodison, S., Stenman, U. H., Hölttä, E. J., Hautaniemi, S., Valmu, L., Lehti, K. I. & Laakkonen, P. M. 2012 In : Journal of Proteomics. 77, p. 87-100 14 p.

    Publication: Contribution to journalA1 Refereed journal article

  9. Anti-Mullerian hormone as a predictor of follicular reserve in ovarian insufficiency: special emphasis on FSH-resistant ovaries

    Kallio, S., Aittomäki, K., Piltonen, T., Veijola, R., Liakka, A., Vaskivuo, T. E., Dunkel, L. & Tapanainen, J. S. 2012 In : Human Reproduction. 27, 3, p. 854-860 7 p.

    Publication: Contribution to journalA1 Refereed journal article

  10. Association between IL6-174G/C and cancer: A meta-analysis of 105,482 individuals

    Liu, R-Y., Song, X., Chen, P., Lei, Z., Miao, J., Yi, N., Zhang, K., Pasche, B. & Zhang, H-T. 2012 In : Experimental and therapeutic medicine. 3, 4, p. 655-664 10 p.

    Publication: Contribution to journalA1 Refereed journal article

  11. Bioinformatic identification of genomic alterations in breast cancer

    Edgren, H. 2012 Helsinki: [H. Edgren]. 75 p.

    Publication: Book/anthologyG5 Doctoral Thesis, articles