Research Program in Genome-Scale Biology

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  1. 2011
  2. Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

    Broeks, A., Schmidt, M. K., Sherman, M. E., Couch, F. J., Hopper, J. L., Dite, G. S., Apicella, C., Smith, L. D., Hammet, F., Southey, M. C., Van 't Veer, L. J., de Groot, R., Smit, V. T. H. B. M., Fasching, P. A., Beckmann, M. W., Jud, S., Ekici, A. B., Hartmann, A., Hein, A., Schulz-Wendtland, R., Burwinkel, B., Marme, F., Schneeweiss, A., Sinn, H-P., Sohn, C., Tchatchou, S., Bojesen, S. E., Nordestgaard, B. G., Flyger, H., Orsted, D. D., Kaur-Knudsen, D., Milne, R. L., Perez, J. I. A., Zamora, P., Menendez Rodriguez, P., Benitez, J., Brauch, H., Justenhoven, C., Ko, Y-D., Hamann, U., Fischer, H-P., Bruening, T., Pesch, B., Chang-Claude, J., Wang-Gohrke, S., Bremer, M., Karstens, J. H., Hillemanns, P., Doerk, T., Nevanlinna, H. A., Heikkinen, T., Heikkilä, P., Blomqvist, C., Aittomäki, K., Aaltonen, K., Lindblom, A., Margolin, S., Mannermaa, A., Kosma, V-M., Kauppinen, J. M., Kataja, V., Auvinen, P., Eskelinen, M., Soini, Y., Chenevix-Trench, G., Spurdle, A. B., Beesley, J., Chen, X., Holland, H., Lambrechts, D., Claes, B., Vandorpe, T., Neven, P., Wildiers, H., Flesch-Janys, D., Hein, R., Loening, T., Kosel, M., Fredericksen, Z. S., Wang, X., Giles, G. G., Baglietto, L., Severi, G., McLean, C., Haiman, C. A., Henderson, B. E., Le Marchand, L., Kolonel, L. N., Alnaes, G. G., Kristensen, V., Borresen-Dale, A-L., Hunter, D. J., Hankinson, S. E., Andrulis, I. L., Mulligan, A. M., O'Malley, F. P., Devilee, P., Huijts, P. E. A., Tollenaar, R. A. E. M., Van Asperen, C. J., Seynaeve, C. S., Chanock, S. J., Lissowska, J., Brinton, L., Peplonska, B., Figueroa, J., Yang, X. R., Hooning, M. J., Hollestelle, A., Oldenburg, R. A., Jager, A., Kriege, M., Ozturk, B., van Leenders, G. J. L. H., Hall, P., Czene, K., Humphreys, K., Liu, J., Cox, A., Connley, D., Cramp, H. E., Cross, S. S., Balasubramanian, S. P., Reed, M. W. R., Dunning, A. M., Easton, D. F., Humphreys, M. K., Caldas, C., Blows, F., Driver, K., Provenzano, E., Lubinski, J., Jakubowska, A., Huzarski, T., Byrski, T., Cybulski, C., Gorski, B., Gronwald, J., Brennan, P., Sangrajrang, S., Gaborieau, V., Shen, C-Y., Hsiung, C-N., Yu, J-C., Chen, S-T., Hsu, G-C., Hou, M-F., Huang, C-S., Anton-Culver, H., Ziogas, A., Pharoah, P. D. P., Garcia-Closas, M. & AOCS, KConFab, Genica Network 2011 In : Human Molecular Genetics. 20, 16, p. 3289-3303 15 p.

    Publication: Contribution to journalA1 Refereed journal article

  3. Male gender is an adverse prognostic factor in B-cell lymphoma patients treated with immunochemotherapy

    Riihijarvi, S., Taskinen, M., Jerkeman, M. & Leppä, S. M. 2011 In : European Journal of Haematology. 86, 2, p. 124-128 5 p.

    Publication: Contribution to journalA1 Refereed journal article

  4. MED12, the Mediator Complex Subunit 12 Gene, Is Mutated at High Frequency in Uterine Leiomyomas

    Mäkinen, N., Mehine, M., Tolvanen, J., Kaasinen, E., Li, Y., Lehtonen, H. J., Gentile, M., Yan, J., Enge, M., Taipale, M., Aavikko, M., Katainen, R., Virolainen, E., Böhling, T., Koski, T. A., Launonen, V., Sjöberg, J., Taipale, J., Vahteristo, P. & Aaltonen, L. A. 2011 In : Science Progress. 334, 6053, p. 252-255 4 p.

    Publication: Contribution to journalA1 Refereed journal article

  5. Membrane-Type-3 Matrix Metalloproteinase (MT3-MMP) Functions as a Matrix Composition-Dependent Effector of Melanoma Cell Invasion

    Tatti, O., Arjama, M., Ranki, A., Weiss, S. J., Keski-Oja, J. & Lehti, K. 2011 In : PLoS One. 6, 12, p. e28325 13 p.

    Publication: Contribution to journalA1 Refereed journal article

  6. Methods for Analysis of Transcription Factor DNA-Binding Specificity In Vitro

    Jolma, A. & Taipale, J. 2011 A Handbook of Transcription Factors. Hughes, T. R. (ed.). Springer Science+Business Media, Vol. 52, p. 155-173

    Publication: Contribution to book/anthologyA3 Contribution to book/other compilations (refereed)

  7. Methylation of H19 and its imprinted control region (H19 ICR1) in Müllerian aplasia

    Sandbacka, M., Bruce, S., Halttunen, M., Puhakka, M., Lahermo, P., Hannula-Jouppi, K., Lipsanen-Nyman, M., Kere, J., Aittomäki, K. & Laivuori, H. 2011 In : Fertility and Sterility : official journal of the American Fertility Society . 95, 8, p. 2703-2706 4 p.

    Publication: Contribution to journalA1 Refereed journal article

  8. MiR-34a Expression Has an Effect for Lower Risk of Metastasis and Associates with Expression Patterns Predicting Clinical Outcome in Breast Cancer

    Peurala, H., Greco, D., Heikkinen, T., Kaur, S., Bartkova, J., Jamshidi, M., Aittomäki, K., Heikkilä, P., Bartek, J., Blomqvist, C., Butzow, R. & Nevanlinna, H. 2011 In : PLoS One. 6, 11, p. e26122 10 p.

    Publication: Contribution to journalA1 Refereed journal article

  9. Missing pattern discovery

    Angelov, S., Inenaga, S., Kivioja, T. & Mäkinen, V. 2011 In : Journal of Discrete Algorithms. 9, 2, p. 153-165 13 p.

    Publication: Contribution to journalA1 Refereed journal article

  10. Molecular mechanisms of tumor suppression by LKB1

    Vaahtomeri, K. & Makela, T. P. 2011 In : FEBS Letters. 585, 7, p. 944-951 8 p.

    Publication: Contribution to journalA2 Review in scientific journal

  11. mRNA-binding protein HuR in breast carcinogenesis

    Heinonen, M. M. 2011 University of Helsinki. (Helsinki University Biomedical Dissertations; no. 151)

    Publication: Book/anthologyG5 Doctoral Thesis, articles